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Glen Research 10-1001說(shuō)明書

更新時(shí)間:2018-08-15      點(diǎn)擊次數(shù):1669

美國(guó)GRC公司:Glen Research Corp 創(chuàng)建于1987年,專注于為DNA和RNA寡核苷酸的化學(xué)合成,修飾,標(biāo)記和純化提供zui廣泛的亞磷酰胺和固體支持物,現(xiàn)已有近三十年的歷史,在低聚核苷酸及修飾、改性領(lǐng)域一直處于地位。

結(jié)構(gòu)研究

以下產(chǎn)品用于研究當(dāng)關(guān)鍵結(jié)構(gòu)元件改變時(shí)對(duì)寡核苷酸活性的影響。7-脫氮嘌呤單體缺乏對(duì)氫鍵合至關(guān)重要的基團(tuán)。7-Deaza-8-aza-A和7-deaza-8-aza-G(PPG)單體是A和G的異構(gòu)體,并且具有相似的電子密度。它們?cè)诠押塑账嶂械拇嬖谙鄬?duì)于A和G略微穩(wěn)定。與G不同,PPG不會(huì)導(dǎo)致聚集,并且可以容易地制備和分離富含G的寡核苷酸。在5'-末端具有PPG的5'-熒光素寡核苷酸比等同的G寡核苷酸淬滅得少得多。作為胸苷的嘌呤類似物,7-脫氮-2'-脫氧黃嘌呤核苷(7-deaza-dX)有望對(duì)三鏈體的DNA結(jié)構(gòu)產(chǎn)生有趣的影響。7-Deaza-dX還與2,4-二氨基嘧啶核苷類似物形成非標(biāo)準(zhǔn)堿基對(duì)。標(biāo)準(zhǔn)核堿基具有未共享的電子對(duì),其突出到雙鏈DNA的小溝中。與DNA,聚合酶,逆轉(zhuǎn)錄酶,限制酶等相互作用的酶可以使用氫鍵供體基團(tuán)與小溝中的氫鍵受體接觸。3-Deaza-2'-deoxyadenosine非常有趣,因?yàn)樗3至顺R?guī)Watson-Crick氫與T鍵合的能力,但缺乏通常由N3提供的3-位的電子對(duì)。

 

 

 

GlenResearch 目錄號(hào):10-1001-xx 

7-Deaza-dA-CE Phosphoramidite
描述:7- Deaza -dA-CE亞磷酰胺

 

5'-二甲氧基三苯甲基-N-苯甲?;?7-脫氮-2'-脫氧腺苷,3' - [(2-氰基乙基) - (N,N-二異丙基)] - 亞磷酰胺

分子式:C 4 8 H 5 3 N 6 O 7 P. 

MW:856.96 

FW:312.22 

 

稀釋劑:無(wú)水乙腈

耦合:合成器制造商推薦的標(biāo)準(zhǔn)方法無(wú)需更改。

去保護(hù):合成器制造商推薦的標(biāo)準(zhǔn)方法無(wú)需更改。

儲(chǔ)存:冷藏,高2-8°C,干燥

溶液中的穩(wěn)定性:類似于dA,C,G,T-CE亞磷酰胺

   

 

10-1001-95

50µm

10-1001-90

100µm

10-1001-02

0.25g

EXTINCTION DATA

Item

Nucleoside

λMax-1

Emax-1

λMax-2

Emax-2

E260

 

 

(nm)

(ml/µmole)

nm

(ml/µmole)

(ml/µmole)

10-1001

7-deaza-dA

270

11.3

 

 

9.4

DILUTION/COUPLING DATA

DILUTION/COUPLING DATA

 

下表顯示了包裝尺寸數(shù)據(jù),以及基于正常灌注程序的溶液,稀釋液和近似偶聯(lián)。請(qǐng)與各種合成器鏈接以獲取更詳細(xì)的使用信息。

 

ABI 392/394

Cat.No.

Pack
Size

Grams/
Pack

0.1M Dil.
(mL)

LV40

LV200

40nm

0.2µm

1µm

10µm

Approximate Number of Additions

10-1001-02

0.25grams

.25grams

2.92

84

50.4

31.5

22.91

16.8

4.2

10-1001-90

100µmoles

.086grams

1

20

12

7.5

5.45

4

1

10-1001-95

50µmoles

.043grams

.5

3.33

2

1.25

.91

.67

.17

Expedite

Cat.No.

Pack
Size

Grams/
Pack

Dilution
(mL)

Molarity

50nm

0.2µm

1µm

15µm

 

Approximate Number of Additions

10-1001-02

0.25grams

.25grams

4.35

.07

80.6

50.38

36.64

5.04

 

10-1001-90

100µmoles

.086grams

1.5

.07

23.6

14.75

10.73

1.48

 

10-1001-95

50µmoles

.043grams

.75

.07

8.6

5.38

3.91

.54

 

 

 

 

貨號(hào)

品名

規(guī)格

目錄價(jià)

品牌

10-0001-02

dA-5'-CE Phosphoramidite

0.25grams

1275

glen research

10-0001-05

dA-5'-CE Phosphoramidite

0.5grams

2550

glen research

10-0001-10

dA-5'-CE Phosphoramidite

1.0gram

5100

glen research

10-0101-02

dC-5'-CE Phosphoramidite

0.25grams

1275

glen research

10-0101-05

dC-5'-CE Phosphoramidite

0.5grams

2550

glen research

10-0101-10

dC-5'-CE Phosphoramidite

1.0gram

5100

glen research

10-0301-02

dT-5'-CE Phosphoramidite

0.25grams

1275

glen research

10-0301-05

dT-5'-CE Phosphoramidite

0.5grams

2550

glen research

10-0301-10

dT-5'-CE Phosphoramidite

1.0gram

5100

glen research

10-1000-02

dA-CE Phosphoramidite

0.25grams

212.5

glen research

10-1000-02M

dA-CE Phosphoramidite

0.25grams

212.5

glen research

10-1000-05

dA-CE Phosphoramidite

0.5grams

425

glen research

10-1000-05M

dA-CE Phosphoramidite

0.5grams

425

glen research

10-1000-10

dA-CE Phosphoramidite

1.0gram

850

glen research

10-1000-10M

dA-CE Phosphoramidite

1.0gram

850

glen research

10-1000-1C

dA-CE Phosphoramidite

1.0gram

850

glen research

10-1000-1S

dA-CE Phosphoramidite

10.0grams

8500

glen research

10-1000-20

dA-CE Phosphoramidite

2.0grams

1700

glen research

10-1000-2C

dA-CE Phosphoramidite

2.0grams

1700

glen research

10-1000-40

dA-CE Phosphoramidite

4.0grams

3400

glen research

10-1000-50

dA-CE Phosphoramidite

5.0grams

4250

glen research

10-1000-5S

dA-CE Phosphoramidite

5.0grams

4250

glen research

10-1000-C2

dA-CE Phosphoramidite

0.25grams

212.5

glen research

10-1000-C5

dA-CE Phosphoramidite

0.5grams

425

glen research

10-1001-02

7-Deaza-dA-CE Phosphoramidite

0.25grams

16575

glen research

10-1001-90

7-Deaza-dA-CE Phosphoramidite

100µmoles

6035

glen research

10-1001-95

7-Deaza-dA-CE Phosphoramidite

50µmoles

3017.5

glen research

10-1002-02

dA+dG-CE Phosphoramidite

0.25grams

680

glen research

10-1003-02

N6-Me-dA-CE Phosphoramidite

0.25grams

8415

glen research

10-1003-90

N6-Me-dA-CE Phosphoramidite

100µmoles

2762.5

glen research

10-1004-02

3'-dA-CE Phosphoramidite

0.25grams

16575

glen research

10-1004-90

3'-dA-CE Phosphoramidite

100µmoles

6035

glen research

10-1004-95

3'-dA-CE Phosphoramidite

50µmoles

3017.5

glen research

10-1006-02

Etheno-dA-CE Phosphoramidite

0.25grams

4335

glen research

10-1006-90

Etheno-dA-CE Phosphoramidite

100µmoles

1785

glen research

10-1007-02

8-Br-dA-CE Phosphoramidite

0.25grams

5015

glen research

10-1007-90

8-Br-dA-CE Phosphoramidite

100µmoles

1955

glen research

10-1008-02

8-oxo-dA-CE Phosphoramidite

0.25grams

6035

glen research

10-1008-90

8-oxo-dA-CE Phosphoramidite

100µmoles

2295

glen research

10-1010-02

dC-CE Phosphoramidite

0.25grams

212.5

glen research

10-1010-02M

dC-CE Phosphoramidite

0.25grams

212.5

glen research

10-1010-05

dC-CE Phosphoramidite

0.5grams

425

glen research

10-1010-05M

dC-CE Phosphoramidite

0.5grams

425

glen research

10-1010-10

dC-CE Phosphoramidite

1.0gram

850

glen research

10-1010-10M

dC-CE Phosphoramidite

1.0gram

850

glen research

10-1010-1C

dC-CE Phosphoramidite

1.0gram

850

glen research

10-1010-1S

dC-CE Phosphoramidite

10.0grams

8500

glen research

10-1010-20

dC-CE Phosphoramidite

2.0grams

1700

glen research

10-1010-2C

dC-CE Phosphoramidite

2.0grams

1700

glen research

10-1010-40

dC-CE Phosphoramidite

4.0grams

3400

glen research

10-1010-50

dC-CE Phosphoramidite

5.0grams

4250

glen research

10-1010-5S

dC-CE Phosphoramidite

5.0grams

4250

glen research

10-1010-C2

dC-CE Phosphoramidite

0.25grams

212.5

glen research

10-1010-C5

dC-CE Phosphoramidite

0.5grams

425

glen research

10-1013-02

dC+dT-CE Phosphoramidite

0.25grams

680

glen research

10-1014-02

pdC-CE Phosphoramidite

0.25grams

4165

glen research

10-1014-05

pdC-CE Phosphoramidite

0.5grams

8330

glen research

10-1014-90

pdC-CE Phosphoramidite

100µmoles

1445

glen research

10-1015-02

Ac-dC-CE Phosphoramidite

0.25grams

212.5

glen research

10-1015-02M

Ac-dC-CE Phosphoramidite

0.25grams

212.5

glen research

10-1015-05

Ac-dC-CE Phosphoramidite

0.5grams

425

glen research

10-1015-05M

Ac-dC-CE Phosphoramidite

0.5grams

425

glen research

10-1015-10

Ac-dC-CE Phosphoramidite

1.0gram

850

glen research

10-1015-10M

Ac-dC-CE Phosphoramidite

1.0gram

850

glen research

10-1015-1C

Ac-dC-CE Phosphoramidite

1.0gram

850

glen research

10-1015-1S

Ac-dC-CE Phosphoramidite

10.0grams

8500

glen research

10-1015-20

Ac-dC-CE Phosphoramidite

2.0grams

1700

glen research

10-1015-2C

Ac-dC-CE Phosphoramidite

2.0grams

1700

glen research

10-1015-40

Ac-dC-CE Phosphoramidite

4.0grams

3400

glen research

10-1015-50

Ac-dC-CE Phosphoramidite

5.0grams

4250

glen research

10-1015-5S

Ac-dC-CE Phosphoramidite

5.0grams

4250

glen research

10-1015-C2

Ac-dC-CE Phosphoramidite

0.25grams

212.5

glen research

10-1015-C5

Ac-dC-CE Phosphoramidite

0.5grams

425

glen research

10-1016-02

TMP-F-dU-CE Phosphoramidite

0.25grams

8415

glen research

10-1016-90

TMP-F-dU-CE Phosphoramidite

100µmoles

3315

glen research

10-1017-02

Pyrrolo-dC-CE Phosphoramidite

0.25grams

11475

glen research

10-1017-90

Pyrrolo-dC-CE Phosphoramidite

100µmoles

3740

glen research

10-1017-95

Pyrrolo-dC-CE Phosphoramidite

50µmoles

1870

glen research

10-1018-02

5-Me-dC Brancher Phosphoramidite

0.25grams

8585

glen research

10-1018-90

5-Me-dC Brancher Phosphoramidite

100µmoles

3485

glen research

10-1019-02

Amino-Modifier C6 dC

0.25grams

7650

glen research

10-1019-90

Amino-Modifier C6 dC

100µmoles

3825

glen research

10-1020-02

dG-CE Phosphoramidite

0.25grams

212.5

glen research

10-1020-02M

dG-CE Phosphoramidite

0.25grams

212.5

glen research

10-1020-05

dG-CE Phosphoramidite

0.5grams

425

glen research

10-1020-05M

dG-CE Phosphoramidite

0.5grams

425

glen research

10-1020-10

dG-CE Phosphoramidite

1.0gram

850

glen research

10-1020-10M

dG-CE Phosphoramidite

1.0gram

850

glen research

10-1020-1C

dG-CE Phosphoramidite

1.0gram

850

glen research

10-1020-1S

dG-CE Phosphoramidite

10.0grams

8500

glen research

10-1020-20

dG-CE Phosphoramidite

2.0grams

1700

glen research

10-1020-2C

dG-CE Phosphoramidite

2.0grams

1700

glen research

10-1020-40

dG-CE Phosphoramidite

4.0grams

3400

glen research

10-1020-50

dG-CE Phosphoramidite

5.0grams

4250

glen research

10-1020-5S

dG-CE Phosphoramidite

5.0grams

4250

glen research

10-1020-C2

dG-CE Phosphoramidite

0.25grams

212.5

glen research

10-1020-C5

dG-CE Phosphoramidite

0.5grams

425

glen research

10-1021-02

7-deaza-dG-CE Phosphoramidite

0.25grams

16575

glen research

10-1021-90

7-deaza-dG-CE Phosphoramidite

100µmoles

6035

glen research

10-1021-95

7-deaza-dG-CE Phosphoramidite

50µmoles

3017.5

glen research

10-1023

dA+dC+dG+dT-CE Phosphoramidite Mix

1.0gram

680

glen research

10-1027-02

8-Br-dG-CE Phosphoramidite

0.25grams

4335

glen research

10-1027-90

8-Br-dG-CE Phosphoramidite

100µmoles

1785

glen research

10-1028-02

8-oxo-dG-CE Phosphoramidite

0.25grams

16575

glen research

10-1028-90

8-oxo-dG-CE Phosphoramidite

100µmoles

6035

glen research

10-1028-95

8-oxo-dG-CE Phosphoramidite

50µmoles

3017.5

glen research

10-1029-02

dmf-dG-CE Phosphoramidite

0.25grams

212.5

glen research

10-1029-02M

dmf-dG-CE Phosphoramidite

0.25grams

212.5

glen research

10-1029-05

dmf-dG-CE Phosphoramidite

0.5grams

425

glen research

10-1029-05M

dmf-dG-CE Phosphoramidite

0.5grams

425

glen research

10-1029-10

dmf-dG-CE Phosphoramidite

1.0gram

850

glen research

10-1029-10M

dmf-dG-CE Phosphoramidite

1.0gram

850

glen research

10-1029-1C

dmf-dG-CE Phosphoramidite

1.0gram

850

glen research

10-1029-1S

dmf-dG-CE Phosphoramidite

10.0grams

8500

glen research

10-1029-20

dmf-dG-CE Phosphoramidite

2.0grams

1700

glen research

10-1029-2C

dmf-dG-CE Phosphoramidite

2.0grams

1700

glen research

10-1029-40

dmf-dG-CE Phosphoramidite

4.0grams

3400

glen research

10-1029-50

dmf-dG-CE Phosphoramidite

5.0grams

4250

glen research

10-1029-5S

dmf-dG-CE Phosphoramidite

5.0grams

4250

glen research

10-1029-C2

dmf-dG-CE Phosphoramidite

0.25grams

212.5

glen research

10-1029-C5

dmf-dG-CE Phosphoramidite

0.5grams

425

glen research

10-1030-02

dT-CE Phosphoramidite

0.25grams

212.5

glen research

10-1030-02M

dT-CE Phosphoramidite

0.25grams

212.5

glen research

10-1030-05

dT-CE Phosphoramidite

0.5grams

425

glen research

10-1030-05M

dT-CE Phosphoramidite

0.5grams

425

glen research

10-1030-10

dT-CE Phosphoramidite

1.0gram

850

glen research

10-1030-10M

dT-CE Phosphoramidite

1.0gram

850

glen research

10-1030-1C

dT-CE Phosphoramidite

1.0gram

850

glen research

10-1030-1S

dT-CE Phosphoramidite

10.0grams

8500

glen research

10-1030-20

dT-CE Phosphoramidite

2.0grams

1700

glen research

10-1030-2C

dT-CE Phosphoramidite

2.0grams

1700

glen research

10-1030-40

dT-CE Phosphoramidite

4.0grams

3400

glen research

10-1030-50

dT-CE Phosphoramidite

5.0grams

4250

glen research

10-1030-5S

dT-CE Phosphoramidite

5.0grams

4250

glen research

10-1030-C2

dT-CE Phosphoramidite

0.25grams

212.5

glen research

10-1030-C5

dT-CE Phosphoramidite

0.5grams

425

glen research

10-1031-02

5'-OMe-dT-CE Phosphoramidite

0.25grams

6035

glen research

10-1031-90

5'-OMe-dT-CE Phosphoramidite

100µmoles

2295

glen research

10-1032-02

O4-Me-dT-CE Phosphoramidite

0.25grams

6035

glen research

10-1032-90

O4-Me-dT-CE Phosphoramidite

100µmoles

2295

glen research

10-1034-02

4-Thio-dT-CE Phosphoramidite

0.25grams

11475

glen research

10-1034-90

4-Thio-dT-CE Phosphoramidite

100µmoles

5015

glen research

10-1034-95

4-Thio-dT-CE Phosphoramidite

50µmoles

2805

glen research

10-1035-02

Carboxy-dT

0.25grams

6120

glen research

10-1035-90

Carboxy-dT

100µmoles

3060

glen research

10-1036-02

2-Thio-dT-CE Phosphoramidite

0.25grams

11475

glen research

10-1036-90

2-Thio-dT-CE Phosphoramidite

100µmoles

5015

glen research

10-1036-95

2-Thio-dT-CE Phosphoramidite

50µmoles

2805

glen research

10-1037-02

Amino-Modifier C2 dT

0.25grams

6120

glen research

10-1037-05

Amino-Modifier C2 dT

0.5grams

12240

glen research

10-1037-90

Amino-Modifier C2 dT

100µmoles

3060

glen research

10-1038-02

Biotin-dT

0.25grams

10625

glen research

10-1038-90

Biotin-dT

100µmoles

5525

glen research

10-1038-95

Biotin-dT

50µmoles

2847.5

glen research

10-1039-02

Amino-Modifier C6 dT

0.25grams

6120

glen research

10-1039-05

Amino-Modifier C6 dT

0.5grams

12240

glen research

10-1039-90

Amino-Modifier C6 dT

100µmoles

3060

glen research

10-1040-02

dI-CE Phosphoramidite

0.25grams

2040

glen research

10-1040-90

dI-CE Phosphoramidite

100µmoles

850

glen research

10-1041-02

2'-DeoxyNebularine-CE Phosphoramidite (Purine)

0.25grams

4335

glen research

10-1041-90

2'-DeoxyNebularine-CE Phosphoramidite (Purine)

100µmoles

1785

glen research

10-1042-02

O6-Phenyl-dI-CE Phosphoramidite

0.25grams

6035

glen research

10-1042-90

O6-Phenyl-dI-CE Phosphoramidite

100µmoles

2295

glen research

10-1044-02

5-Nitroindole-CE Phosphoramidite

0.25grams

5525

glen research

10-1044-90

5-Nitroindole-CE Phosphoramidite

100µmoles

2125

glen research

10-1046-02

2-Aminopurine-CE Phosphoramidite

0.25grams

6035

glen research

10-1046-90

2-Aminopurine-CE Phosphoramidite

100µmoles

2295

glen research

10-1047-02

dP-CE Phosphoramidite

0.25grams

10115

glen research

10-1047-90

dP-CE Phosphoramidite

100µmoles

3315

glen research

10-1048-02

dK-CE Phosphoramidite

0.25grams

10115

glen research

10-1048-90

dK-CE Phosphoramidite

100µmoles

3315

glen research

10-1049-02

dP+dK-CE Phosphoramidite

0.25grams

10115

glen research

10-1049-90

dP+dK-CE Phosphoramidite

100µmoles

3315

glen research

10-1050-02

dU-CE Phosphoramidite

0.25grams

1700

glen research

10-1050-90

dU-CE Phosphoramidite

100µmoles

595

glen research

10-1051-02

O4-Triazolyl-dU-CE Phosphoramidite

0.25grams

6035

glen research

10-1051-90

O4-Triazolyl-dU-CE Phosphoramidite

100µmoles

2295

glen research

10-1052-02

4-Thio-dU-CE Phosphoramidite

0.25grams

11475

glen research

10-1052-90

4-Thio-dU-CE Phosphoramidite

100µmoles

5015

glen research

10-1052-95

4-Thio-dU-CE Phosphoramidite

50µmoles

2805

glen research

10-1053-02

5-OH-dU-CE Phosphoramidite

0.25grams

11475

glen research

10-1053-90

5-OH-dU-CE Phosphoramidite

100µmoles

3825

glen research

10-1054-02

pdU-CE Phosphoramidite

0.25grams

3315

glen research

10-1054-05

pdU-CE Phosphoramidite

0.5grams

6630

glen research

10-1054-90

pdU-CE Phosphoramidite

100µmoles

1105

glen research

10-1055-02

2'-deoxypseudoU-CE Phosphoramidite

0.25grams

16575

glen research

10-1055-90

2'-deoxypseudoU-CE Phosphoramidite

100µmoles

6035

glen research

10-1055-95

2'-deoxypseudoU-CE Phosphoramidite

50µmoles

3017.5

glen research

10-1056-02

Fluorescein-dT Phosphoramidite

0.25grams

11475

glen research

            

 

 

 

上海起發(fā)實(shí)驗(yàn)試劑有限公司是實(shí)驗(yàn)試劑一站式采購(gòu)服務(wù)商

1:強(qiáng)大的進(jìn)口輻射能力,血清、抗體、耗材、大部分限制進(jìn)口品等。

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5:多年積累良好的信譽(yù),大部分客戶提供貨到付款服務(wù)??蛻舭ㄇ迦A、北大、交大、復(fù)旦、中山等100多所高校,ROCHE,阿斯利康、國(guó)藥、fisher等知藥企。

6:我們還是Santa,Advanced Biotechnologies Inc,Athens Research & Technology,bangs,BBInternational,crystalchem,dianova,FD Neurotechnologies,Inc. FormuMax Scientific,Inc, Genebridege, Glycotope Biotechnology GmbH; iduron,Innovative Research of America, Ludger, neuroprobe,omicronbio, Polysciences,prospecbi, QA-BIO,quickzyme,RESEARCH DIETS,INC,sterlitech;sysy,TriLink BioTechnologies,Inc;worthington-biochem,zyagen等幾十家國(guó)外公司授權(quán)代理。

7:我們還是invitrogen,qiagen,MiraiBioam,sigma;neb,roche,merck, rnd,BD, GE,pierce,BioLegend等知*批發(fā),歡迎合作。

 

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