美國TopoGEN公司成立于1991年,是一家診斷公司,由一批在拓撲異構(gòu)酶領(lǐng)域工作和在基礎、臨床、應用及相關(guān)方面研究經(jīng)驗豐富的研究者創(chuàng)建,為以藥物開發(fā)為基礎的拓撲異構(gòu)酶和機制研發(fā)人員提供創(chuàng)新產(chǎn)品和服務。藥物篩選試劑盒可以分析拓撲異構(gòu)酶活性藥物,用于癌癥化療和抗菌方面。TopoGEN公司還能提供原核和真核化驗拓撲異構(gòu)酶 (I型,II,IV和旋轉(zhuǎn)酶)檢測試劑盒,體外體內(nèi)診斷均可應用。TopoGEN公司還提供DNA載體、DNA裂解目標、拓撲異構(gòu)酶抑制劑、拓撲異構(gòu)酶抗體和相關(guān)試劑盒等完整產(chǎn)品線。
TopoGEN授權(quán)書-上海起發(fā)
topogen產(chǎn)品目錄:
貨號 | 品名 | 規(guī)格 |
TG2000H-1 | Human Topoisomerase IIa | 250 units |
TG2000H-2 | Human Topoisomerase IIa | 500 units |
TG2000H-3 | Human Topoisomerase IIa | 1000 units |
TG2000H-4 | Human Topoisomerase IIa | 2000 units |
TG2005H-RC1 | Human Topoisomerase I | 250 units |
TG2005H-RC2 | Human Topoisomerase I | 500 units |
TG2005H-RC3 | Human Topoisomerase I | 3000 units |
TG2005H-Y723F | Mutant Human Topoisomerase I (Y723F) | 10ug |
TG2000G-1 | E. coli DNA Gyrase | 100 units |
TG2000G-3 | E. coli DNA Gyrase | 500 units |
TG2000G-5 | E. coli DNA Gyrase | 1000 units |
TG2000G-7 | E. coli DNA Gyrase | 2000 units |
TG2000GSA-1 | S. aureus DNA Gyrase | 100 units |
TG2000GSA-3 | S. aureus DNA Gyrase | 500 units |
TG2000GSA-5 | S. aureus DNA Gyrase | 1000 units |
TG2000EC-1 | E. coli Topoisomerase IV | 250 units |
TG2000EC-3 | E. coli Topoisomerase IV | 500 units |
TG2000EC-5 | E. coli Topoisomerase IV | 1000 units |
TG1050-1 | Topoisomerase Type IIa Nuclear Extraction/Assay Kit | 100 assays |
TG1001-1 | Topoisomerase II Assay Kit (20ug kDNA) | 100 assays |
TG1001-2 | Topoisomerase II Assay Kit (50ug kDNA) | 250 assays |
TG1001-1A | Topoisomerase II Assay Kit (20ug kDNA + 100u Human Topo Iia) | 100 assays |
TG1001-2A | Topoisomerase II Assay Kit (50ug kDNA + 250u Human Topo Iia) | 250 assays |
TG1001-3A | Topoisomerase II Assay Kit (100ug kDNA + 500u Human Topo Iia) | 500 assays |
TG1009-1 | Topoisomerase II Drug Screening Kit (25ug SC DNA) | 100 assays |
TG1009-2 | Topoisomerase II Drug Screening Kit (62.5ug SC DNA) | 250 assays |
TG1009-1A | Topoisomerase II Drug Screening Kit (25ug SC DNA + 100u Topo Iia) | 100 assays |
TG1009-2A | Topoisomerase II Drug Screening Kit (62.5ug SC DNA + 250u Topo Iia) | 250 assays |
TG1009-3A | Topoisomerase II Drug Screening Kit (62.5ug SC DNA + 500u Topo Iia) | 250 assays |
TG1019-1 | Topoisomerase II Drug Screening Kit (20ug kDNA) | 100 assays |
TG1019-2 | Topoisomerase II Drug Screening Kit (50ug kDNA) | 250 assays |
TG1019-1A | Topoisomerase II Drug Screening Kit (20ug kDNA + 100u Human Topo Iia) | 100 assays |
TG1019-2A | Topoisomerase II Drug Screening Kit (50ug kDNA + 250u Human Topo Iia) | 250 assays |
TG1019-3A | Topoisomerase II Drug Screening Kit (50ug kDNA + 500u Human Topo Iia) | 250 assays |
TG1022 | Topo II In Vivo Link Kit | 200 assays |
TG1007-1 | E. coli Topoisomerase IV Drug Screening Kit (25ug SC DNA) | 100 assays |
TG1007-2 | E. coli Topoisomerase IV Drug Screening Kit (62.5ug SC DNA) | 250 assays |
TG1007-1A | E. coli Topoisomerase IV Drug Screening Kit (25ug SC DNA + 100u EC Topo IV) | 100 assays |
TG1007-2A | E. coli Topoisomerase IV Drug Screening Kit (62.5ug SC DNA + 250u EC Topo IV) | 250 assays |
TG1007-3A | E. coli Topoisomerase IV Drug Screening Kit (62.5ug SC DNA + 500u EC Topo IV) | 250 assays |
TG1008-1 | E. coli Topo IV Drug Screening Kit (20ug kDNA) | 100 assays |
TG1008-2 | E. coli Topo IV Drug Screening Kit (50ug kDNA) | 250 assays |
TG1008-1A | E. coli Topo IV Drug Screening Kit (20ug kDNA + 100u E. coli Topo IV) | 100 assays |
TG1008-2A | E. coli Topo IV Drug Screening Kit (50ug kDNA + 250u E. coli Topo IV) | 250 assays |
TG1008-3A | E. coli Topo IV Drug Screening Kit (50ug kDNA + 500u E. coli Topo IV) | 250 assays |
TG1040-1 | Topoisomerase Type I Nuclear Extraction/Assay Kit | 100 assays |
TG1015-1 | Topoisomerase I Assay Kit (25ug SC DNA) | 100 assays |
TG1015-2 | Topoisomerase I Assay Kit (62.5ug SC DNA) | 250 assays |
TG1015-1A | Topoisomerase I Assay Kit (25ug SC DNA +100u Human Topo I) | 100 assays |
TG1015-2A | Topoisomerase I Assay Kit (62.5ug SC DNA + 250u Human Topo I) | 250 assays |
TG1015-3A | Topoisomerase I Assay Kit (125ug SC DNA + 500u Human Topo I) | 500 assays |
TG1018-1 | Topoisomerase I Drug Screening Kit (25ug SC DNA) | 100 assays |
TG1018-2 | Topoisomerase I Drug Screening Kit (62.5ug SC DNA) | 250 assays |
TG1018-1A | Topoisomerase I Drug Screening Kit (25ug SC DNA + 100u Human Topo I) | 100 assays |
TG1018-2A | Topoisomerase I Drug Screening Kit (62.5ug SC DNA + 250u Human Topo I) | 250 assays |
TG1018-3A | Topoisomerase I Drug Screening Kit (62.5ug SC DNA + 500u Human Topo I) | 250 assays |
TG1021 | Topoisomerase I In Vivo Link Kit | 200 assays |
TG1017-1 | Human Topoisomerase I High Load Kit | 500 units |
TG1017-2 | Human Topoisomerase I High Load Kit | 1000 units |
TG1010-1 | In Vitro SDS-K+ Precipitation Kit | 100 assays |
TG1010-2 | In Vitro SDS-K+ Precipitation Kit | 250 assays |
TG1025 | DNA Intercalator/Unwinding Kit | 50 experiments |
TG1011-1 | In Vivo SDS-K+ Precipitation Kit | 100 assays |
TG1011-2 | In Vivo SDS-K+ Precipitation Kit | 250 assays |
TG1020-0 | Human Topoisomerase I ICE Assay Kit (No Antibody) | 24 Tests |
TG1020-1 | Human Topoisomerase I ICE Assay Kit | 24 Tests |
TG1020-2a | Human Topoisomerase IIa ICE Assay Kit | 24 Tests |
TG1020-2b | Human Topoisomerase IIb ICE Assay Kit | 24 Tests |
TG1020-3a | Human Topoisomerase IIIa ICE Assay Kit | 24 Tests |
TG1020-3b | Human Topoisomerase IIIb ICE Assay Kit | 24 Tests |
TG1030-1 | Human Topoisomerase I EMSA Kit | 25 assays |
TG1030-2 | Human Topoisomerase II EMSA Kit | 25 assays |
TG1003 | DNA Gyrase Assay Kit | 100 assays |
TG2000G-1KIT | Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (50ug Relaxed DNA + 100u Gyrase) | 100 assays |
TG2000G-3KIT | Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (250ug Relaxed DNA + 500u Gyrase) | 500 assays |
TG2000G-5KIT | Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (500ug Relaxed DNA + 1000u Gyrase) | 1000 assays |
TG2000G-7KIT | Purified E. coli DNA Gyrase and Relaxed DNA Assay Kit (1mg Relaxed DNA + 2000u Gyrase) | 2000 assays |
TG2001G-1KIT | Purified E. coli DNA Gyrase Drug Screening Kit (50ug Relaxed DNA + 100u Gyrase) | 100 assays |
TG2001G-3KIT | Purified E. coli DNA Gyrase Drug Screening Kit (250ug Relaxed DNA + 500u Gyrase) | 500 assays |
TG2001G-5KIT | Purified E. coli DNA Gyrase Drug Screening Kit (500ug Relaxed DNA + 1000u Gyrase) | 1000 assays |
TG2001G-7KIT | Purified E. coli DNA Gyrase Drug Screening Kit (1mg Relaxed DNA + 2000u Gyrase) | 2000 assays |
TG2017-1 | Mouse Monoclonal Antibody to Human Topoisomerase I (Covalent Complex) | 100 units |
TG2017-2 | Mouse Monoclonal Antibody to Human Topoisomerase I (Covalent Complex) | 250 units |
TG2011-5 | Mouse Monoclonal Antibody to Human Topo IIB | 100 units |
TG1024-A | Topoisomerase IIa Band Shift Kit | 25 assays |
TG1024-B | Topoisomerase IIb Band Shift Kit | 25 assays |
TG2010-1 | Mouse Monoclonal Antibody to Human Topoisomerase IIα | 50 units |
TG2011-1 | Rabbit Polyclonal Antibody to Human Topoisomerase IIα | 250 units |
TG2010-3 | Rabbit Polyclonal Antibody to Human Topoisomerase IIb | 250 units |
TG2012 | Human Antibody to Human Topoisomerase I (Scleroderma Serum) | 500 units |
TG2012-2 | Rabbit Polyclonal Antibody to Human Topoisomerase I (Rabbit Serum) | 250 ul |
TG2012-4 | Mouse Monoclonal Antibody to Human Topoisomerase I | 100 ug |
TG2014 | Rabbit Polyclonal Antibody to Yeast Topo II (Serum) | 250 ul |
TG2010-4 | Rabbit Polyclonal Antibody to Human Topoisomerase IIIb | 250 units |
TG2015 | Mouse Monoclonal Antibody to Human Topoisomerase IIIα | 50 ul |
TG2011-2 | Topoisomerase IIα C-terminal Peptide | 50 ug |
TG2011-3 | Topoisomerase IIα MW Marker | 20 units |
TG2011-4 | Topoisomerase I WB Marker | 20 units |
TG1030 | Topoisomerse II Immunofluorescence Kit | >50 analyses |
TG1035 | Topoisomerase II Immunoprecipitation Kit | >50 analyses |
TG1004-1 | Human TDP1 Assay Kit (Oligo) | 100 assays |
TG1004-1A | Human TDP1 Assay Kit (DNA/* Complex) | 100 assays |
TG1004-2 | Human TDP1 Assay Kit (Oligo) | 250 assays |
TG1004-2A | Human TDP1 Assay Kit (DNA/* Complex) | 250 assays |
TG2004H-1 | Human TDP1 Protein | 250 units |
TG2004H-2 | Human TDP1 Protein | 500 units |
TG2016 | Rabbit Polyclonal Antibody to Human TDP1 | 250 units |
TG2038-1 | Human TDP2 DNA Substrate | 10 ug |
TG2038-3 | Human TDP2 DNA Substrate | 50 ug |
TG1005-1 | Human TDP2 Assay Kit | 100 assays |
TG1005-2 | Human TDP2 Assay Kit | 250 assays |
TG2003H-1 | Human TDP2 Protein | 25 ug |
TG2003H-2 | Human TDP2 Protein | 50 ug |
TG2013-1 | Kinetoplast DNA (catenated) | 25 ug |
TG2013-2 | Kinetoplast DNA (catenated) | 50 ug |
TG2013-3 | Kinetoplast DNA (catenated) | 250 ug |
TG2018-1 | Linear Kinetoplast DNA Marker | 10 ug |
TG2020-1 | Decatenated Kinetoplast DNA Marker | 10 ug |
TG2023-2 | pRYG DNA (topo II target site) | 20 ug |
TG2025-1 | Relaxed pRYG DNA Marker | 10 ug |
TG2028-1 | Linear pRYG DNA Marker | 10 ug |
TG2030-1 | Supercoiled pHOT-1 DNA | 25 ug |
TG2030-2 | Supercoiled pHOT-1 DNA | 50 ug |
TG2030-3 | Supercoiled pHOT-1 DNA | 250 ug |
TG2030-4 | Supercoiled pHOT-1 DNA | 500 ug |
TG2035-1 | Relaxed pHOT-1 DNA | 25 ug |
TG2035-2 | Relaxed pHOT-1 DNA | 50 ug |
TG2035-3 | Relaxed pHOT-1 DNA | 250 ug |
TG2035-4 | Relaxed pHOT-1 DNA | 500 ug |
DR3000 HRHeLa-Sce | HR based Kit in HeLa Requiring I-Sce1 Transfection | ea |
DR3000 HRHeLa-CPR | HR based Kit in HeLa Requiring CRISPR Transfection | ea |
DR3000 HRCN1.4-Sce | HR based Kit in Mouse Neuronal Cells Requiring I-Sce1 Transfection | ea |
DR3000 HRSH-Sce | HR in human Neuroblastoma Cells req. I-Sce1 Transfection | ea |
DR3000 HR3T3-Sce | HR based Kit in MOUSE 3T3 Cells Requiring I-Sce1 Transfection | ea |
DR3000 Custom-Sce | Customer makes own cell line hosting HR Reporter (I-Sce Transfectn req.) Includes HRHeLa cell line control | ea |
DR3000A Custom-Sce | Customer makes own cell line hosting HR Reporter (I-Sce Transfectn req.) No HRHeLa cell line control | ea |
DR5001 HNHela-Sce | NHEJ Based HeLa Requires I-Sce1 Transfection | ea |
DR5000 HNSH-Sce | NHEJ Based in Human Neuroblastoma Line requires I-Sce1 transfection | ea |
DR5000 HNCN1.4-Sce | NHEJ Based in Mouse Neuronal CN1.4 cells requires I-Sce1 transfection | ea |
DR5000 HN3T3-Sce | NHEJ Based Mouse 3T3 cells Requires I-Sce1 Transfection | ea |
DR5000 Custom-Sce | Customer creates cell line hosting NHEJ Reporter (I-Sce Transfectn req.) Includes iHNHeLa cell line control | ea |
DR5000A Custom-Sce | Customer creates cell line hosting NHEJ Reporter (I-Sce Transfectn req.) NO iHNHeLa cell line control | ea |
DR7001 LE-HE | HeLa Cell Reporters to detect DNA Methylation (DM) Effectors: Hypomethylating and Hypermethylating Effectors | ea |
DR7001 LE | HeLa Cell Reporters to detect DNA Hypomethylating Effectors | ea |
DR7001 HE | HeLa Cell Reporters to detect DNA Hypermethylating Effectors | ea |
TG4110 | Camptothecin 10mM | 0.25ml |
TG4120 | Doxorubicin 10mM | 0.25ml |
TG4130 | Daunomycin 10mM | 0.25ml |
TG4140 | Etoposide 10mM | 0.25ml |
TG4150 | m-AMSA 10mM | 0.25ml |
TG4160 | Genistein 10mM | 0.25ml |
TG4170 | Ellipticine 10mM | 0.25ml |
TG4180 | Ciproflaxin | 50 ul |
TG4100 | Topotecan 10mM | 0.25ml |
TG4101 | Irinotecan 10mM | 0.25ml |
TG4102 | 9-Nitro-20 (S) Camptothecin 10mM | 0.25ml |
TG4103 | 10-Hydroxy Camptothecin 10 mM | 0.25ml |
TG4104 | 9-amino-CPT 10mM (0.25ml) | 0.25ml |
TG4010 | Topo I Assay Buffer 10x | 1ml |
TG4030 | Gyrase Assay Buffer 5x | 1ml |
TG4032 | 5x Topoisomerase IV Assay Buffer (2-part) | 1ml |
TG4040 | Topo II Assay Buffer (2 part) | 1ml |
TG4060 | 10% SDS | 1ml |
TG4065 | Sarkosyl 20% | 5ml |
TG4037 | 5x Stop Buffer | 1ml |
TG4038 | 10x Gel Loading Buffer | 1ml |
TG4039 | 10x Proteinase K | 0.5ml |
TG4035 | 20mM ATP | 0.5ml |
TG4045 | 5X SA Gyrase Assay Buffer | 1ml |
TG4055 | 5X Potassium Glutamate | 1ml |
TG4090 | Topoisomerase II Dilution Buffer | 1ml |
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