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HMGBIOTECH DISULFIDE HMGB1說明書

更新時(shí)間:2024-03-15      點(diǎn)擊次數(shù):425

HMGBIOTECH   高遷移率蛋白、質(zhì)粒、抗體


hmgbiotech HM-120

HMGB 1是細(xì)胞核的一個(gè)組成部分,在基因組的組織和表達(dá)中具有多種功能。HMG生物技術(shù)SRL為活躍在這一領(lǐng)域的其他研究人員和公司提供試劑、服務(wù)和想法。它還有助于實(shí)驗(yàn)室開發(fā)分析和試劑。


hmgbiotech  DISULFIDE HMGB1說明書


hmgbiotech HM-120


HMGB1是一種核蛋白,其由壞死細(xì)胞被動釋放,由凋亡細(xì)胞保留,并由炎癥細(xì)胞主動分泌(Dumitriu等人,HMGB1:從內(nèi)部引導(dǎo)免疫。Trends Immunol 2005,26:381-7)。HMGB1對生命至關(guān)重要:HMGB1基因敲除小鼠出生后不久死亡。

HMGB1作為運(yùn)動細(xì)胞的化學(xué)引誘劑和細(xì)胞因子的誘導(dǎo)劑的兩種不同活性被歸因于不同的生物化學(xué)形式。還原的HMGB1(具有化學(xué)引誘活性的形式)被還原;二硫化物HMGB1包含C23和C45之間的二硫鍵(完整注釋:HMGB1C23-C45C106h–Antoine J.等人(2014)。Mol-Med)。

二硫化物HMGB1可誘導(dǎo)單核細(xì)胞和其他炎癥細(xì)胞產(chǎn)生細(xì)胞因子和趨化因子(Venereau等人,2012)。

在結(jié)構(gòu)上,二硫化物HMGB1在半胱氨酸殘基23和45與還原的半胱氨酸殘基106之間具有二硫鍵。測試二硫化物HMGB1刺激細(xì)胞因子的能力




HMGBiotech公司熱銷產(chǎn)品

產(chǎn)品名稱

貨號

100 ug Fully reduced HMGB1, LPS free

HM-115

50 ug Fully reduced HMGB1, LPS free

HM-116

100 ug Disulfide HMGB1, LPS free

HM-121

100 ug BoxA from HMGB1, LPS-free and tested in migration assay

HM-012

50 ug Disulfide HMGB1, LPS free

HM-122

500 ug BoxA from HMGB1, LPS-free and tested in migration assay

HM-013

1 mg HMGB1 for biochemistry

HM-100

2.5 mg BoxA from HMGB1, LPS-free and tested in migration assay

HM-014

250 ug HMGB1 biochemistry

HM-101

25 ug BoxA from HMGB1, LPS-free and tested in migration assay

HM-011

15 ug BoxB from HMGB1, LPS-free and tested in migration assay

HM-053

15 ug Fully reduced HMGB1, LPS free

HM-117

10 ug Disulfide HMGB1, LPS free

HM-123

15 ug Non-oxidizable HMGB1, LPS free

HM-133

250 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration

HM-170

100 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration

HM-171

50 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration

HM-172

15 ug Stromal Cell-Derived Factor 1α (SDF-1α, CXCL12) tested in migration

HM-173

50 ug HMGB1 15N labelled for Mass Spectrometry

HM-180

5 ug HMGB1 15N labelled for Mass Spectrometry

HM-181

2.5 mg BoxA 2D from HMGB1, LPS-free and tested in migration assay

HM-190

500 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay

HM-191

100 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay

HM-192

25 ug BoxA 2D from HMGB1, LPS-free and tested in migration assay

HM-193

Control cell lysates from Hmgb1 +/+

HM-001

Control cell lysates from Hmgb1 -/-

HM-002

1 mg BoxB from HMGB1, LPS-free and tested in migration assay

HM-050

250 ug BoxB from HMGB1, LPS-free and tested in migration assay

HM-051

100 ug BoxB from HMGB1, LPS-free and tested in migration assay

HM-052

500 ug Fully reduced HMGB1, LPS free

HM-114

250 ug Disulfide HMGB1, LPS free

HM-120

500 ug Non-oxidizable HMGB1, LPS free

HM-130

100 ug Non-oxidizable HMGB1, LPS free

HM-131

50 ug Non-oxidizable HMGB1, LPS free

HM-132

500 ug HMGB2, LPS-free and tested in migration assay

HM-151

100 ug HMGB2, LPS-free and tested in migration assay

HM-152

50 ug HMGB2, LPS-free and tested in migration assay

HM-153

Embryonic fibroblasts immortalized with large T antigen. One vial of -/- cells and one vial of +/+ cells

HM-201

Embryonic fibroblasts immortalized with the 3T3 method. One vial of -/- cells and one vial of +/+ cells

HM-221

Embryonic fibroblasts, Hmgb1-/- and HMGB2-low, immortalized with the 3T3 method. One vial of cells, and

HM-223

HMGB1 Isoforms Kit - Test size

HM-030

Embryonic fibroblasts immortalized with the 3T3 method. One vial of Hmgb2-/- cells and one vial of +/+ cells

HM-251

HMGB1 Isoforms Kit - Regular size

HM-031

20 ug p-mHMG1

HM-300

50 ug Terminally oxidized HMGB1, LPS free

HM-062

20 ug p-mHMG1tag

HM-301

100 ug Terminally oxidized HMGB1, LPS free

HM-061

20 ug pEGFP-HMGB1

HM-302

250 ug Terminally oxidized HMGB1, LPS free

HM-060

20 ug pcDNA/FL-RAGE plasmid

HM-310



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