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Enzyme Research 是一家擁有超過25年的酶研究的實驗室,生產和開發(fā)多種用于基本凝血研究的多種酶和輔因子。在過去的十年Enzyme Research Laboratories為科學家參與止血和血栓形成的研究提供了寶貴支持。Enzyme Research通過不斷追求產品的zui高品質,贏得了世界各地凝血研究實驗室的信任。
HFXIa 1111a Human Factor XIa
Prepared from Human Factor XI using Human Factor Xlla. This Xlla was removed using a corn trypsin inhibitor column. Complete activation is observed by SDS-PAGE. Factor XI, through the contact factor pathway cascade, is activated to Factor XIa via Factor Xlla and High Molecular Weight Kininogen. During activation by Factor Xlla and HK, FXI undergoes proteolytic cleavage in which the Mr=80,000 chain reportedly is cleaved to a heavy and light chain with Mr of about 48,000 and 33,000. This Factor XIa is responsible for the activation of Factor IX to Factor IXa. Unlike other examples of activation of Vitamin K-dependent blood-clotting proteins, Factor XIa proteolysis of Factor IX does not require membrane surfaces.
Buffer composition = 4 mM Sodium Acetate-HCl/0.15 M NaCl/pH 5.3
*Extinction Coefficient (1%) = 13.1
Molecular Weight = 160,000 daltons上海起福生物科技有限公司:楊建輝:辦公:*8006::http://gygcedu.com/地址:上海市浦東新區(qū)繡川路561號1102室
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